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Men's sexual issues like impotence and erectile dysfunction are also treated with cenforce 50. Only men over the age of 18 are allowed to use this medication. Sildenafil Citrate is a component in the medication that helps men's penile tissue receive more blood flow and has the effect of relaxing the muscle tissue there. In order to fully enjoy your sex with your partner, take this medication half an hour prior to sexual activity. You can take this medication with or without food. Do not break or chew this medication; instead, take it with water. This medication takes 36 hours to take effect.