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Lorazepam binds to stereospecific benzodiazepine receptors on postsynaptic GABA neurons, increasing the permeability of neuronal membranes to Cl-ions. The GABA inhibitory actions that lead to hyperpolarization and stability are enhanced as a result. A common medicine called ativan, also referred to as lorazepam, is used to treat anxiety disorders, seizures, and insomnia.
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